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Hormone & Longevity
Second line — by exceptionNot a controlled substanceCompounded by a 503A pharmacy

Sermorelin

Growth hormone releasing hormone analogue

Sermorelin stimulates your own pituitary to release growth hormone in natural pulses. It sits in Category 1 of the FDA interim 503A bulk substances list and was withdrawn commercially in 2008 for business rather than safety reasons.

This is not where treatment usually starts. It is prescribed when the manufactured, FDA-approved option has been ruled out for you specifically, and your nurse practitioner has to write down why before it can be sent to a pharmacy. You are welcome to ask about it — just expect the conversation.

Regulatory status

Compounded drug. Not FDA-approved. Sermorelin is a component of a previously FDA-approved product.

Restorative sleep and recovery

Frequency

Nightly injection, 5 nights weekly

Route

Subcutaneous

Supply

4-week patient-specific supply

Minimum age

21+

What it does

What patients get from this

  • Supports deeper slow-wave sleep
  • Preserves lean mass during weight loss
  • Physiologic pulsatile release rather than exogenous GH
  • Improved recovery between training sessions

We will not prescribe this if

  • Active malignancy
  • Current pregnancy or breastfeeding
  • Untreated hypothyroidism
  • Proliferative diabetic retinopathy

The intake asks about each of these. Some answers stop the process; others are flagged for your nurse practitioner.

Labs your NP may order

  • IGF-1
  • CMP
  • TSH
  • HbA1c

Draw at our Fort Lauderdale clinic or a reference lab near you. Your NP reviews the results and posts them to your account.

Please read

  • Compounded drugs are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
  • Filled in your name and shipped to the clinic for you. Never drawn from a shared supply.

About compounded medication

A compounded preparation is made for one named patient by a licensed pharmacy. It is not an FDA-approved product: the FDA does not review it for safety, effectiveness or manufacturing quality. Your nurse practitioner has to record a specific clinical reason why the commercially available product will not work for you before this can be prescribed — and cost on its own is not one.

A 503A pharmacy may not supply a clinic with shared stock, so your prescription is filled in your name and shipped to the clinic for you. A nurse cannot administer it without linking the order it came from.